How to Choose a Fertility Clinic & When to Get a Second Opinion

Choosing a fertility clinic is one of the most important decisions you'll make on your path to parenthood. The right clinic can mean the difference between success and failure, between feeling supported and feeling like a number. And if your current clinic isn't working, knowing when and how to switch — or at least get a second opinion — can change everything.

This guide helps you evaluate clinics, understand success rates, recognize red flags, ask the right questions, and know when it's time for a fresh perspective.

What Makes a Good Fertility Clinic?

Beyond success rates (which we'll discuss in detail), several factors contribute to a clinic's quality:

Medical Excellence

Patient Experience

Practical Considerations

Understanding Success Rates

Success rates are the first thing most people look at — and the most commonly misunderstood metric in fertility care.

Why You Can't Simply Compare Clinic Success Rates

The CDC and SART publish clinic-specific success rates, and it's tempting to pick the clinic with the highest numbers. But this approach is flawed:

⚠️ Patient Selection Bias

Clinics that accept harder cases (older patients, poor prognosis, repeated failures) will have lower average success rates. Clinics that turn away difficult patients will look better on paper. A clinic with 60% success might actually be better than one with 70% if the first accepts everyone while the second cherry-picks.

SART explicitly warns against using their data to compare clinics. The CDC data comes with similar caveats. These databases are useful for understanding national trends, not for picking your specific clinic.

Better Metrics to Ask About

Live Birth Rate Per Cycle Started

This is the most meaningful number. It counts everyone who began treatment, including those who canceled or didn't make it to transfer. Pregnancy rate or clinical pregnancy rate can be misleading because they don't account for miscarriages.

Implantation Rate

The percentage of transferred embryos that implant. This is arguably the best quality metric because it reflects embryo and lab quality. Ask for this number specifically for patients your age.

Multiple Pregnancy Rate

Lower is actually better. High multiple rates suggest the clinic transfers too many embryos to boost success numbers, which increases risks for mothers and babies.

Embryo Thaw Survival Rate

Should be 95% or higher with modern vitrification. Lower rates suggest lab quality issues.

Age-Specific Results

Always ask for success rates broken down by age. National averages for live birth per cycle started:

Age Live Birth Rate (Per Cycle)
Under 35 ~44-50%
35-37 ~36-40%
38-40 ~22-27%
41-42 ~10-15%
43+ ~3-5%

Your clinic's numbers for your age group are more relevant than their overall average.

The SART Patient Predictor Tool

SART offers a tool at sartcorsonline.com that provides personalized cumulative success estimates based on your specific factors. This can give you a realistic sense of your chances over multiple cycles.

Red Flags to Watch For

Some warning signs should make you think twice about a clinic:

đźš© Major Red Flags

Green Flags That Indicate Quality

âś“ Signs of a Good Clinic

Essential Questions to Ask

Before committing to a clinic, ask these questions:

About Success Rates

"What is your live birth rate per cycle started for patients my age?"

Not pregnancy rate, not per transfer — per cycle started. This is the most honest number.

"What is your implantation rate for my age group?"

This reflects embryo and lab quality most directly.

"What percentage of your patients my age achieve live birth within 3 cycles?"

Cumulative success rate is often more relevant than per-cycle rate.

About Your Care

"Will I see the same doctor throughout my treatment?"

Continuity matters. At minimum, you should have a primary RE who knows your case.

"Who performs the egg retrieval and embryo transfer?"

Is it your doctor or whoever is on call? The RE performing transfer matters.

"What happens after a failed cycle? Do we have a review meeting?"

Good clinics automatically schedule post-cycle consultations to analyze and adjust.

About the Lab

"Is your lab accredited? By whom?"

Look for CAP (College of American Pathologists) or JCAHO accreditation.

"What is your embryo thaw survival rate?"

Should be 95% or higher. Lower rates indicate potential lab quality issues.

"How many embryologists do you have, and how long have they been with you?"

Experienced, stable embryology teams produce better outcomes.

About Costs

"Can I get a complete cost breakdown including all possible fees?"

Medications, monitoring, retrieval, transfer, ICSI, PGT-A, freezing, storage, FET — everything.

"What's included versus additional costs?"

Is ICSI standard or extra? What about assisted hatching? Embryo freezing?

When to Consider Switching Clinics

Loyalty is admirable, but sometimes a change is needed. Consider switching or at least getting a second opinion if:

After Multiple Failed Cycles

The probability of IVF success decreases after 3-4 failed cycles. If you've had 3 or more failed cycles without explanation or meaningful protocol changes, a fresh perspective may help.

Studies show pregnancy rates decrease about 40% after 4 or more attempts. This isn't a reason to give up, but it is a reason to reassess strategy.

Communication Breakdown

If you can't get answers to your questions, feel dismissed when raising concerns, or simply don't trust your doctor's judgment anymore, the relationship isn't working. Your fertility care is too important for a broken doctor-patient relationship.

No Protocol Adjustments

If your clinic keeps doing the same thing after failure without any changes, they're not learning from your cycles. Good medicine involves adaptation.

Significant Errors

Repeated scheduling mistakes, medication errors, miscommunication about critical timing — these aren't just inconveniences. They can affect your outcome and indicate systemic problems.

Your Gut Says So

Sometimes you just know. If you've lost confidence in your clinic, that matters. You need to trust your medical team during this vulnerable time.

How to Get a Second Opinion

Getting a second opinion is standard medical practice. Good doctors expect and welcome it. Here's how to approach it:

You Don't Need Permission

You don't have to tell your current clinic you're seeking another opinion. Your medical records are yours — you're entitled to copies. Most patients don't mention it until/unless they decide to switch.

Gather Your Records

Request copies of:

What to Expect

Second opinion consultations typically cost $200-$500. Many clinics offer free virtual consultations for new patients. Come prepared with questions and your records.

A good second opinion will offer:

đź’ˇ Virtual Consultations

Many clinics now offer telemedicine second opinions. This is especially useful for exploring international options or clinics far from home. You can gather perspectives from multiple experts without travel.

Evaluating International Clinics

If you're considering treatment abroad — including Colombia — additional factors come into play:

Accreditation and Standards

Communication

Logistics

Colombia-Specific Considerations

Colombia offers several advantages for international patients:

Considering a Second Opinion?

We can connect you with Colombian fertility specialists for a free consultation to review your case and discuss your options.

Get Free Consultation

Making the Final Decision

After gathering information, trust your assessment of:

Medical Competence

Does the clinic have experienced doctors, skilled embryologists, and a track record of success for patients like you? Are they up-to-date on current best practices?

Communication Fit

Do you feel heard? Are your questions answered? Can you reach someone when you need to? Do you trust this team with something so important?

Practical Alignment

Does the cost work for you? Is the location manageable? Do their hours accommodate your schedule?

Your Instinct

After all the research, how do you feel? Your gut reaction matters. You're going to be vulnerable with these people during one of the most stressful experiences of your life. Choose a team you trust.

The Bottom Line

Choosing a fertility clinic deserves careful consideration — it's not a decision to make based on advertising, convenience alone, or even just published success rates. Look at the whole picture: medical expertise, lab quality, communication, cost, and how you feel about the team.

Don't be afraid to ask hard questions. Don't be afraid to get second opinions. Don't be afraid to switch if something isn't working. This is your journey, and you deserve a clinic that treats you as a partner, not just a patient.

The right clinic won't guarantee success — nothing can. But it will give you the best possible chance while supporting you through whatever comes.

Read more: After a Failed IVF Cycle | Understanding Fertility Tests | IVF Cost Guide