🔬 Key Facts About Male Fertility
- Male factor contributes to 40-50% of infertility cases
- Sperm quality can be improved in 2-3 months with lifestyle changes
- ICSI has revolutionized treatment for severe male factor
- DNA fragmentation matters even when standard parameters look good
- Age affects sperm too—quality declines after 40
Fertility discussions often focus on eggs and ovaries, but sperm health is equally important. Men contribute half the genetic material, and sperm quality directly impacts fertilization, embryo development, and pregnancy success.
The good news? Unlike egg quality, sperm quality can often be improved with lifestyle changes—and IVF techniques like ICSI can overcome many male factor challenges.
of infertility cases involve male factor—alone or combined with female factors
Understanding Your Semen Analysis
The semen analysis (SA) is the cornerstone of male fertility testing. Here's what the numbers mean:
| Parameter | WHO Reference (2021) | What It Means |
|---|---|---|
| Volume | ≥1.4 mL | Total amount of ejaculate |
| Concentration | ≥16 million/mL | Sperm per milliliter |
| Total Count | ≥39 million | Total sperm in ejaculate |
| Motility | ≥42% moving | Percentage that swim |
| Progressive Motility | ≥30% | Swimming forward effectively |
| Morphology | ≥4% normal forms | Properly shaped sperm |
📊 Important Context
These are reference values, not guarantees. Men with below-reference values can father children naturally, and men with "normal" values can have fertility issues. The SA is a starting point, not the whole picture.
What Different Results Mean for IVF
- Normal parameters: Standard IVF or ICSI both viable options
- Low count/motility: ICSI recommended—only need one good sperm per egg
- Very low count (<5 million): Severe oligospermia—ICSI essential
- No sperm in ejaculate: Azoospermia—may need surgical sperm retrieval (TESE/micro-TESE)
- Poor morphology alone: Often less significant—ICSI can select best-looking sperm
Beyond the Semen Analysis: DNA Fragmentation
Standard semen analysis doesn't assess DNA integrity. Sperm can look normal but carry damaged DNA that affects:
- Fertilization rates
- Embryo development
- Implantation success
- Miscarriage risk
When to Test for DNA Fragmentation
- Unexplained infertility
- Recurrent pregnancy loss
- Repeated IVF failure with good embryos
- Poor embryo development despite good eggs
- Age over 45
- Varicocele
- History of infection, fever, or toxic exposures
💡 The Good News About DNA Fragmentation
Unlike many female fertility issues, high DNA fragmentation can often be improved through lifestyle changes, antioxidant supplementation, varicocele repair, or using testicular sperm (which has lower fragmentation than ejaculated sperm).
ICSI: The Game-Changer for Male Factor
Intracytoplasmic Sperm Injection (ICSI) revolutionized treatment for male infertility. Instead of placing sperm around an egg and hoping for fertilization, a single sperm is injected directly into each egg.
ICSI allows pregnancy even with:
- Very low sperm counts
- Poor motility (even immotile sperm can work)
- Abnormal morphology
- Surgically retrieved sperm
- Previously frozen sperm
Success rates with ICSI are excellent—fertilization rates of 70-80% are typical, comparable to standard IVF with normal sperm.
Surgical Sperm Retrieval
For men with no sperm in the ejaculate (azoospermia), sperm can often be retrieved directly from the testicle:
- TESE (Testicular Sperm Extraction): Small tissue sample taken from testicle
- Micro-TESE: Microscope-guided extraction for better precision
- PESA/MESA: Aspiration from epididymis (for obstructive azoospermia)
These procedures, combined with ICSI, allow biological fatherhood for many men previously told it was impossible.
Improving Sperm Quality
Unlike eggs (which you're born with), sperm are continuously produced. The sperm you produce today started developing ~74 days ago. This means lifestyle changes now can improve sperm quality in 2-3 months.
✅ Do These
- Exercise moderately: 30+ minutes, 3-5x/week
- Eat antioxidant-rich foods: Colorful vegetables, fruits, nuts
- Maintain healthy weight: BMI 20-25 optimal
- Get adequate sleep: 7-8 hours nightly
- Manage stress: Cortisol affects testosterone
- Stay cool: Loose underwear, avoid hot tubs
- Take supplements: CoQ10, zinc, folate, vitamin D
❌ Avoid These
- Smoking: Damages sperm DNA significantly
- Heavy alcohol: >14 drinks/week impairs quality
- Recreational drugs: Especially marijuana, anabolic steroids
- Excessive heat: Hot baths, saunas, laptop on lap
- Testosterone supplements: Actually STOP sperm production
- Certain medications: Check with doctor
- Excessive cycling: >5 hours/week may affect quality
⚠️ Critical Warning: Testosterone Therapy
If you're on testosterone replacement therapy (TRT), stop immediately and consult a fertility specialist. External testosterone signals your body to stop producing sperm. This is often reversible but can take 6-12 months. Never start TRT if you want children without discussing alternatives.
Supplements That May Help
Research supports several supplements for sperm health:
| Supplement | Typical Dose | Evidence |
|---|---|---|
| CoQ10 | 200-600mg daily | Improves motility and concentration |
| Zinc | 25-50mg daily | Essential for testosterone and sperm production |
| Folate | 400-800mcg daily | Supports DNA synthesis |
| Vitamin D | 2000-4000 IU daily | Associated with better motility |
| Omega-3s | 1-2g daily | Supports sperm membrane integrity |
| L-Carnitine | 2-3g daily | May improve motility |
| Selenium | 55-100mcg daily | Antioxidant protection |
Start supplements 2-3 months before IVF for maximum benefit.
Male Age and Fertility
While men can father children much later than women can conceive, male age does matter:
- After 40: Sperm quality begins declining—more DNA damage, lower motility
- After 45: Time to pregnancy increases; miscarriage rates higher
- After 50: Higher rates of certain conditions in offspring (autism, schizophrenia)
The effect is gradual and less dramatic than female age, but it exists. Couples where both partners are older face compounded challenges.
What to Expect on IVF Day
On egg retrieval day, you'll need to provide a sperm sample. Here's how to optimize it:
- Abstinence: 2-5 days beforehand (not longer—quality declines)
- Collection: Usually at the clinic in a private room
- Backup plan: If performance anxiety is a concern, discuss freezing a sample in advance
- Lab processing: Sperm is washed and concentrated for fertilization
When Male Factor Is Severe
For the most challenging cases, additional options exist:
- Micro-TESE: Finding sperm even in non-obstructive azoospermia
- Testicular sperm: Often has lower DNA fragmentation than ejaculated
- Donor sperm: When own sperm isn't available or viable
- PGT-A: Can identify embryos despite sperm issues
Even severe male factor rarely means fatherhood is impossible with today's technology.
Supporting Your Partner
IVF is often harder on women physically, but men play a crucial role:
- Attend appointments: Be present for consultations and procedures when possible
- Learn the process: Understand what she's going through
- Handle injections: Many partners administer the shots
- Manage logistics: Take on extra household tasks
- Emotional support: Listen without trying to fix everything
- Take care of yourself: Your wellbeing matters too
Male Fertility Testing in Colombia
All standard and advanced male fertility testing is available in Colombia:
- Semen analysis: ~$50-100
- DNA fragmentation testing: ~$150-300
- Hormone panel (testosterone, FSH, LH): ~$100-200
- Genetic testing: Available if indicated
- TESE/Micro-TESE: ~$1,500-3,000 (vs. $5,000-15,000 US)
Get a Complete Male Fertility Evaluation
Don't overlook male factor. Our partner clinics offer comprehensive testing and treatment for all aspects of sperm health.
Request Free ConsultationThe Bottom Line
Male fertility matters—and the encouraging news is that many male factor issues are either treatable or can be overcome with IVF/ICSI. Key takeaways:
- Get tested early: Semen analysis is simple and informative
- Lifestyle changes work: 2-3 months of optimization can improve quality
- ICSI is powerful: Even severe male factor is often surmountable
- DNA fragmentation: Consider testing if standard parameters are normal but you're struggling
- You're in this together: Your support matters as much as your sperm
Your contribution is half the equation—make it count. 💪